Biochemical Aspects of Methanol Poisoning

Evaluation of Clinical and Biochemical Variables in Acute Methanol Poisoning: Is blood pH a Good Prognostic Factor for Prediction of Outcome?

Background: Acute methanol poisoning is one of the most important chemical poisoning due to drinking of illegal and handmade alcoholic beverages in Iran. The aim of this study was to evaluate clinical and biochemical parameters as prognostic factor in acute methanol poisoning. Methods: A retrospective study was performed on acute methanol poisoning cases admitted to the Loghman Hakim Hospital P...

Biochemistry of methanol poisoning. 4. The effect of methanol and its metabolites on retinal metabolism.

Methanol poisoning.

A 22-year-old male presented with acute onset vomiting, diarrhea, abdominal pain and altered sensorium. He had a history of acute alcohol intake (locally made with solvent) a day prior to the presentation. Biochemical investigations revealed severe metabolic acidosis. Diagnosis of methanol poisoning was made on the basis of history and biochemical abnormality. Magnetic resonance imaging (MRI) d...

Uncoventional Views on Certain Aspects of Toxin-Induced Metabolic Acidosis

This discussion will highlight the following 9 specific points that related to metabolic acidosis caused by various toxins. The current recommendation suggests that alcohol dehydrogenase inhibitor fomepizole is preferred to ethanol in treatment of methanol and ethylene glycol poisoning, but analysis of the enzyme kinetics indicates that ethanol is a better alternative. In the presence of a mode...

Epidemics/Outbreaks of Methanol Poisoning

Epidemics of methanol poisoning happen across the globe. There are prognostic factors associated with morbidity or mortality from methanol poisoning. Recently we have compared retrospective observational case series of methanol-poisoned patients from Norway (1979 and 2002-2005), Estonia (2001) and Tunisia (2003/2004), and patients from two different centers in Iran (Teheran 2004-2009 and Mashha...